Prima – Celiac Test (1 Test)
Prima – Celiac Test (1 Test)
CELIAC DISEASE
Celiac Disease (CD), also known as “celiac sprue”, is a chronic inflammatory disorder of the small intestine, produced by the ingestion of dietary gluten products in susceptible people. It is a multifactorial disease, including genetic and environmental factors. Environmental trigger is represented by gluten while the genetic predisposition has been identified in the major histocompatibility complex region which causes the presence of specific antibodies against gluten and its components.
Celiac disease is not a rare disorder like previously thought, with a global prevalence around 1%. The reason of its under recognition is mainly referable to the fact that about half of affected people do not have the classic gastrointestinal symptoms, but they present nonspecific manifestations nutritional deficiency or have no symptoms at all.
Prima – Celiac Test (1 Test)
CELIAC DISEASE
Celiac Disease (CD), also known as “celiac sprue”, is a chronic inflammatory disorder of the small intestine, produced by the ingestion of dietary gluten products in susceptible people. It is a multifactorial disease, including genetic and environmental factors. Environmental trigger is represented by gluten while the genetic predisposition has been identified in the major histocompatibility complex region which causes the presence of specific antibodies against gluten and its components.
Celiac disease is not a rare disorder like previously thought, with a global prevalence around 1%. The reason of its under recognition is mainly referable to the fact that about half of affected people do not have the classic gastrointestinal symptoms, but they present nonspecific manifestations nutritional deficiency or have no symptoms at all.
GLUTEN, GLIADIN AND DGP
Gluten is a protein found in wheat, composed of glutenin and gliadin. It helps foods maintain their shape, acting as a
glue that holds food together. Gliadin is a peptide water-soluble component of gluten and it can pass through the intestinal
epithelium. Gliadin is the part of gluten responsible for Celiac Disease. DGP: Deamidated gliadin peptides are the
result of the action of Transglutaminase Enzyme and its detection could increase sensitivities, specificities and accuracies of celiac disease screening.
Tag: Test, celiac, gluten, gastro
Information
WHO ARE THE INTENDED USERS
Patients with symptoms (abdominal bloating and pain, chronic diarrhea, vomiting, constipation, weight loss, fatigue, irritability), patients with a first-degree family member with CD, and people with Type I diabetes.
WHY – BENEFITS
Underdiagnosis is common and the quality-of-life impact of symptoms may be severe. Checking the presence of specific antibodies against DGP is a useful tool to detect Celiac disease.
TEST PRINCIPLE
CELIAC TEST is based on an immunochromatographic reaction. If the antibodies (IgA and IgG) are present into the sample, they will react with the deamidated gliadin. A positive result means that the concentration of antibodies is nearby to 20 AU/mL.
How to take test
Content: 1 hermetically sealed aluminium pouch containing: 1 device for the CELIAC TEST and a desiccant bag; 1 transparent plastic bag containing a pipette for collecting blood; 1 vial with dropper containing the CELIAC TEST diluent required for 1 test; 2 pain-free , sterile lancing devices for obtaining a blood sample; 1 alcohol cleansing gauze and 1 instructions for use -leaflet.
Warning: Keep out of the reach of children
**Disclaimer**: This home test kit is intended for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Results may vary based on individual conditions and should be discussed with a healthcare provider. Always follow the test instructions carefully and do not use past the expiration date. The manufacturer is not liable for incorrect results due to improper use or storage of the product.
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